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Category Archives: Bioethics

The Clock Keeps Ticking

September 19, 2016

Just how long should the wait be before assuming that an answer to an important question will never be provided? It depends of course on the importance of the issue and the credibility of both the individual who is asking the question and the individual who is supposed to respond. In a letter written on …more»

Is Anyone Listening?

September 12, 2016

In July, 2016 a letter was sent to 14 Institutional Review Boards (IRBs) declaring that they had incorrectly approved a study of VRC01 HIV monoclonal antibody in infants at high risk of HIV infection. The study would withhold lifesaving treatment from the infants until after the experimental monoclonal antibody was administered. Several IRBs replied that …more»

Too Many Research Products. Too Few Research Volunteers. Ethical Implications

August 3, 2016

The financial and infrastructure investment in clinical research over the past several decades has resulted in major benefits to the health of individuals in both wealthy and poor countries. The ability to identify the cause of disease and develop treatments to control and even eradicate disease is a testimony to the investment in clinical research …more»

An Ethical Collision Course

June 6, 2016

Physicians in Clinical Research and Physicians in Clinical Care Research physicians dedicated to finding the cause, prevention, and treatment of diseases may find themselves in a position of conflict of interest when conducting research in income poor countries. As new and exciting treatment discoveries proliferate and are coupled with dramatic increases in funds for clinical …more»

The VRC01 Study Must Be Stopped Now

April 11, 2016

Modified April 24, 2016 First Tuskegee, then Guatemala, and now VRC01 In April, 2016 NIH initiated a study of the HIV broadly neutralizing monoclonal antibody (bNAb) VRC01. The study mimics two infamous studies, Tuskegee and Guatemala, universally declared unethical for withholding effective treatment from sexually transmitted infections in disadvantaged populations. (1-3) As if the memory …more»