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Category Archives: Bioethics

Is Anyone Listening?

September 12, 2016

In July, 2016 a letter was sent to 14 Institutional Review Boards (IRBs) declaring that they had incorrectly approved a study of VRC01 HIV monoclonal antibody in infants at high risk of HIV infection. The study would withhold lifesaving treatment from the infants until after the experimental monoclonal antibody was administered. Several IRBs replied that …more»

Too Many Research Products. Too Few Research Volunteers. Ethical Implications

August 3, 2016

The financial and infrastructure investment in clinical research over the past several decades has resulted in major benefits to the health of individuals in both wealthy and poor countries. The ability to identify the cause of disease and develop treatments to control and even eradicate disease is a testimony to the investment in clinical research …more»

An Ethical Collision Course

June 6, 2016

Physicians in Clinical Research and Physicians in Clinical Care Research physicians dedicated to finding the cause, prevention, and treatment of diseases may find themselves in a position of conflict of interest when conducting research in income poor countries. As new and exciting treatment discoveries proliferate and are coupled with dramatic increases in funds for clinical …more»

The VRC01 Study Must Be Stopped Now

April 11, 2016

Modified April 24, 2016 First Tuskegee, then Guatemala, and now VRC01 In April, 2016 NIH initiated a study of the HIV broadly neutralizing monoclonal antibody (bNAb) VRC01. The study mimics two infamous studies, Tuskegee and Gautama, universally declared unethical for withholding effective treatment from sexually transmitted infections in disadvantaged populations. (1-3) As if the memory …more»

The Calculus of Human Value

March 23, 2016

How is it Determined? In the opening of the 1998 movie A Civil Action, John Travolta plays the protagonist, an aggressive Boston attorney. The film and a book of the same name are based on a true story of a court case about environmental pollution of water that took place in Woburn, Massachusetts, in the …more»