Skip to Content

Category Archives: International and National Clinical Research

The Bioethical Duty to Warn and the Resurgence of Sexually Transmitted Diseases.

November 17, 2018

The recent Centers for Disease Control and Prevention (CDC)  report on dramatic increases in sexually transmitted infections (STIs) in the US is alarming. (N.Y. Times. August 28, 2018. Data from the CDC shows that for the last four years new infections of chlamydia, gonorrhea, and syphilis have risen sharply to a record of more …more»

Do Ask. Do Tell

January 16, 2018

In public health, contact tracing is the identification and diagnosis of people who may have come into contact with an infected person. Historically contact tracing has been the mainstay for controlling epidemics caused by infectious agents regardless of the means of spread. However, contact tracing for HIV has not been universally employed to prevent the …more»

Just When You Thought It Couldn’t Be Worse. A Look Behind the Scenes

February 2, 2017

The results of clinical research studies are often published without details of the scientific and ethical discussions that precede their final approval. The Children with HIV Early Antiretroviral Therapy (CHER) study initiated in 2005 and conducted in South Africa is a case in point.1 The study sought to evaluate immediate versus delayed treatment of infants …more»

The Clock Keeps Ticking

September 19, 2016

Just how long should the wait be before assuming that an answer to an important question will never be provided? It depends of course on the importance of the issue and the credibility of both the individual who is asking the question and the individual who is supposed to respond. In a letter written on …more»

Is Anyone Listening?

September 12, 2016

In July, 2016 a letter was sent to 14 Institutional Review Boards (IRBs) declaring that they had incorrectly approved a study of VRC01 HIV monoclonal antibody in infants at high risk of HIV infection. The study would withhold lifesaving treatment from the infants until after the experimental monoclonal antibody was administered. Several IRBs replied that …more»